A NOVEL THIRD-GENERATION EGFR TYROSINE KINASE INHIBITOR ABIVERTINIB FOR EGFR T790M-MUTANT NON–SMALL CELL LUNG CANCER: A MULTICENTER PHASE I/II STUDY
In this phase I/II trial, the authors investigated a novel third-generation EGFR tyrosine kinase inhibitor (TKI), abivertinib, in patients with non-small cell lung cancer and harboring the T790M resistance mutation. Abivertinib demonstrated favorable efficacy and a tolerable safety profile in patients. Specifically among the 209 patients evaluated, the objective response rate (ORR) was 52.2% (95% […]
