Mutation mismatch repair gene deletions in diffuse large B-cell lymphoma.
To further unravel the molecular pathogenesis of diffuse large B-cell lymphoma (DLBCL), a high-resolution comparative genomic hybridization on lymph node biopsies from 70 patients was performed. With this strategy, microdeletions of genes involved in the mutation mismatch repair (MMR) pathway were identified in two samples. The first patient presented a homozygous deletion of MSH2-MSH6 due […]
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