July 4, 2016

Until recently, if you wanted to know how a tumour was evolving, you had to take a biopsy of the cancer tissue and analyse it in a lab. This was clearly an invasive method for the patient, requiring a puncture, incision or surgery, and you could not use it to track the disease’s progression. Now, […]

In a recent study, molecular biomarkers were identified from an international discovery set of 673 medulloblastoma cases from the Medulloblastoma Advanced Genomics International Consortium. Risk stratification models were designed based on combined clinical and cytogenetic biomarkers identified in multivariable Cox proportional hazards analyses. Candidate biomarkers were tested using fluorescence in situ hybridization (FISH) on a